Background. Informed consent (IC) is not only a regulatory but also an ethical requirement to participate in any clinical trial. It is essential to determine that research participants understand what they consent to. Studies that evaluate participants’ understanding of IC conclude that recall and understanding of IC is often low, and researchers recommend that interactive multimedia interventions should be implemented to optimise understanding. Objectives. To assess participants’ understanding of IC of the research trial that they agreed to participate in.Methods. A (...) descriptive survey design, within a quantitative research approach, was used to conduct the study at two government hospitals in the Eastern Cape Province. A semi-structured, self-administered questionnaire was used to collect information from 170 participants in research studies. Descriptive statistics were used to analyse the results.Results. Participants were recruited from among women who enrolled in any of the three studies that were ongoing at the two sites during the recruitment period. The study participants had a mean age of 25.9 years. Nearly one-third (30%) could not recall the purpose of the original trial that they consented to. The concept of randomisation was not understood by any of the participants.Conclusion. Regardless of extensive efforts to ensure that participants understood their participation, this study unveiled poor recall of essential information on IC. It is proposed that IC should be short and only address essential components such as purpose, procedure, possible risks or benefits, alternative options if not participating and explaining the concept of voluntary participation. (shrink)

This collection of essays is concerned with the present world struggle between totalitarianism and the western heritage of freedom. Its contributors are well-known economists, sociologists, philosophers and political scientists from the United States and Europe. It is dedicated "to the moral and intellectual struggle against communism and an analysis of our own democratic institutions." The purpose of the book is both clarification and inspiration. The essays cover such subjects as the nature of freedom in the West, the common patrimony of (...) America and Europe, the role of the masses in representative democracy, intellectualism and political impotence.--V. G. P. (shrink)

This work of vast erudition, which according to the author is substantially the same as the original Swedish edition, attempts to show how the young Augustine integrated certain key concepts of ancient philosophy into Christian thought. Holte limits himself to the philosophical issues and so does not consider the young Augustine as theologian. Parts I and II develop the historical background of the concept telos in the ancient philosophers and in the early Fathers. Part III presents the central thesis: that (...) Augustine tried to link the contemplative life to the commandment of love which requires total abandonment to God of every form of human life. The Telos is to be found in the contemplative life, although Augustine never separates it from the active. Telos is to be realized in the study of Christian philosophy and scripture. Part IV treats of this realization as a sort of Christian gnosis which can be briefly characterized from the point of view of systematic theology as fides quaerens intellectum.--V. G. P., S.J. (shrink)

A short, not too technical introduction to the existentialist movement. The first half of the book presents five basic themes which existentialists treat in a distinctive way: the problems of knowledge, reality, existence, communication, and transcendence. The second half of the book gathers together five independent lectures on Kierkegaard, Heidegger, Jaspers, Sartre and Marcel. The book is useful for those unacquainted with the men and their ideas.--V. G. P.

This collection of essays is concerned with the present world struggle between totalitarianism and the western heritage of freedom. Its contributors are well-known economists, sociologists, philosophers and political scientists from the United States and Europe. It is dedicated "to the moral and intellectual struggle against communism and an analysis of our own democratic institutions." The purpose of the book is both clarification and inspiration. The essays cover such subjects as the nature of freedom in the West, the common patrimony of (...) America and Europe, the role of the masses in representative democracy, intellectualism and political impotence.--V. G. P. (shrink)

This textbook of Thomistic metaphysics is based on the author's conviction that metaphysics is founded in sense experience. Fidelity to Aristotle and Aquinas on this point entails, according to the author, certain departures from the more usual presentation of systematized Thomism. This second edition is more readable, adds to the English bibliography, and amends the presentation of the doctrine of analogy, presenting it in a less rigid and over-refined way.--V. G. P.

This work of scholarship examines the use of the Greek terms epistrephein and epistrophë by pagan and Christian writers during the first three centuries A.D. Such a study, though philological, intends also to contrast two distinct attitudes toward human existence: fidelity to oneself and fidelity to God. The findings include the following: 1) these terms appear in the common language of the period in a non-technical sense, 2) the Christian use of them has a Biblical origin, 3) the philosophical use (...) of the terms is of uncertain origin, 4) the expression epistrephein eis eauton is philosophical and not truly Christian, 5) the notion of "conversio Dei" is alien to pagan thought, and 6) these divergent uses had an influence on the mystical traditions of paganism and Christianity.--V. G. P. (shrink)

This little book is a collection of essays on the philosophy of mind and serves as a preview of a larger work to come. Writing from the point of view of naturalism, while not defending it, Langer is primarily concerned with the relation of the human mind to feeling, which is the subject of the first essay, "The Process of Feeling." Other contributions include speculations on the origin of speech, a new definition of symbol, the cultural importance of art, the (...) relation of the individual to society. Interesting and provocative.--V. G. P. (shrink)

This small volume is one of the series entitled "Contemporary Perspectives in Philosophy." It contains eight essays which fall into two groups: 1) the first five deal with the Austin-Strawson debate revolving around Austin's modified "correspondence theory," 2) the last three, two of which are by Strawson, and the other by Dummett commenting on Strawson. The editor has provided a useful bibliography.--V. G. P.

An impressive book whose purpose is to "relate the outstanding events of contemporary life and thought to the accumulated wisdom of the past." Forming part of the series The Great Books of the Western World, its contributors are among the most qualified in their fields: Alfred Kazin, George Gamow, Irving Kristol, Karl Ubell, and James Collins, not to mention the editors themselves. Five parts make up the book: in Part I, The Great Debate of the Year: "Does America's best hope (...) for the future lie in political conservatism?", Barry Goldwater speaks for the affirmative and Jacob Javits for the negative; Part II, The Editors' Review of the Year, analyzes three problems as yet unsolved: the divided world, automation, and television; Part III, the largest portion of the work, reviews the contemporary scene in literature, physical science and technology, social sciences and law, biology and medicine, and philosophy and religion ; Part IV offers four important additions to the Great Books Library: M. Luther's The Freedom of a Christian, R. H. Tawney's The Acquisitive Society, Max Planck's The Universe in the Light of Modern Physics, and James Joyce's The Dead; finally, Part V gives a bibliography of significant books published in the last ten years.--V. G. P., S. J. (shrink)

According to the author, philosophy and politics are intimately connected, since any understanding of society involves an analysis of "order." The notion of order contains three essential elements which political philosophers have frequently overlooked: unity, sanction and authority. Barth examines the work of Burke, Rivarol, de Lamennais, Comte and others. The concluding chapter attempts to resolve the problems raised by the apparent conflict between "historical" and "natural" right in a comprehensive idea of order.--V. G. P.

The major portion of the book presents the biological facts, while the final chapter raises philosophical questions concerning 1) the antithesis between form and substance, 2) the relation of form to aesthetics, and 3) the origin of mind in the goal-seeking quality of life. The author does not pretend to solve the questions he raises; he merely wishes to draw attention to them "at a time when many people fail to recognize them, and when even some biologists have temporarily lost (...) sight of the fundamental importance of the fact of form for the science of life."--V. G. P. (shrink)

A clear, concise and well-organized textbook in Thomistic metaphysics which incorporates recent developments in "Thomistic Existentialism," while retaining the best of the traditional content. Each chapter concludes with a summary and a list of supplementary readings. As a textbook, it succeeds in stressing the essentials and, at the same time, by judicious use of footnotes, indicates what are still issues among Thomists. The book represents the position of that group of Neo-Thomist thinkers who emphasize the primacy of existence and the (...) actual over essence and the possible as the object of metaphysics. A good introduction to the subject.--V. G. P. (shrink)

The objectives of this study were to develop a high-density chromosome bin map of homoeologous group 7 in hexaploid wheat, to identify gene distribution in these chromosomes, and to perform comparative studies of wheat with rice and barley. We mapped 2148 loci from 919 EST clones onto group 7 chromosomes of wheat. In the majority of cases the numbers of loci were significantly lower in the centromeric regions and tended to increase in the distal regions. The level of duplicated loci (...) in this group was 24% with most of these loci being localized toward the distal regions. One hundred nineteen EST probes that hybridized to three fragments and mapped to the three group 7 chromosomes were designated landmark probes and were used to construct a consensus homoeologous group 7 map. An additional 49 probes that mapped to 7AS, 7DS, and the ancestral translocated segment involving 7BS also were designated landmarks. Landmark probe orders and comparative maps of wheat, rice, and barley were produced on the basis of corresponding rice BAC/PAC and genetic markers that mapped on chromosomes 6 and 8 of rice. Identification of landmark ESTs and development of consensus maps may provide a framework of conserved coding regions predating the evolution of wheat genomes. (shrink)

This study examines BDI logics in the context of Gabbay's fibring semantics. We show that dovetailing can be adopted as a semantic methodology to combine BDI logics. We develop a set of interaction axioms that can capture static as well as dynamic aspects of the mental states in BDI systems, using Catach's incestual schema G^[a, b, c, d]. Further we exemplify the constraints required on fibring function to capture the semantics of interactions among modalities. The advantages of having a fibred (...) approach is discussed in the final section. (shrink)

Starting from a connected, partially ordered set of events, it is shown that results of the measurement of time are elements of a partially ordered and filtering field, as used in a previous paper. Moreover, some relations between physical formulas and properties of the field are proved. Finally, some open problems and suggestions are pointed out. For the convenience of the reader not acquainted with elementary algebraic methods, proofs are given in detail.

To localize wheat ESTs on chromosomes, 882 homoeologous group 6-specific ESTs were identified by physically mapping 7965 singletons from 37 cDNA libraries on 146 chromosome, arm, and sub-arm aneuploid and deletion stocks. The 882 ESTs were physically mapped to 25 regions flanked by 23 deletion breakpoints. Of the 5154 restriction fragments detected by 882 ESTs, 2043 were localized to group 6 chromosomes and 806 were mapped on other chromosome groups. The number of loci mapped was greatest on chromosome 6B and (...) least on 6D. The 264 ESTs that detected orthologous loci on all three homoeologs using one restriction enzyme were used to construct a consensus physical map. The physical distribution of ESTs was uneven on chromosomes with a tendency toward higher densities in the distal halves of chromosome arms. About 43% of the wheat group 6 ESTs identified rice homologs upon comparisons of genome sequences. Fifty-eight percent of these ESTs were present on rice chromosome 2 and the remaining were on other rice chromosomes. Even within the group 6 bins, rice chromosomal blocks identified by 1-6 wheat ESTs were homologous to up to 11 rice chromosomes. These rice-block contigs were used to resolve the order of wheat ESTs within each bin. (shrink)

Despite traditionally being characterised as a melancholy thinker with a propensity to dwell on existential anxiety, sin and despair, scholarly interest in the place of love in Søren Kierkegaard’s ethical thought is currently gaining significant traction. In particular, Kierkegaard’s Works of Love has increasingly come under the academic spotlight as a text with potentially rich and previously underappreciated insights for Christian ethics. This article aims to contribute to this ongoing illumination, by highlighting the moral psychology and theological anthropology of Kierkegaard’s (...) Christian lover in discourses II–V of Works of Love’s second series. In doing this, I aim to put forward an overarching ethical framework which can be seen to structure these moral deliberations. (shrink)

A total of 1918 loci, detected by the hybridization of 938 expressed sequence tag unigenes from 26 Triticeae cDNA libraries, were mapped to wheat homoeologous group 4 chromosomes using a set of deletion, ditelosomic, and nulli-tetrasomic lines. The 1918 EST loci were not distributed uniformly among the three group 4 chromosomes; 41, 28, and 31% mapped to chromosomes 4A, 4B, and 4D, respectively. This pattern is in contrast to the cumulative results of EST mapping in all homoeologous groups, as reported (...) elsewhere, that found the highest proportion of loci mapped to the B genome. Sixty-five percent of these 1918 loci mapped to the long arms of homoeologous group 4 chromosomes, while 35% mapped to the short arms. The distal regions of chromosome arms showed higher numbers of loci than the proximal regions, with the exception of 4DL. This study confirmed the complex structure of chromosome 4A that contains two reciprocal translocations and two inversions, previously identified. An additional inversion in the centromeric region of 4A was revealed. A consensus map for homoeologous group 4 was developed from 119 ESTs unique to group 4. Forty-nine percent of these ESTs were found to be homoologous to sequences on rice chromosome 3, 12% had matches with sequences on other rice chromosomes, and 39% had no matches with rice sequences at all. Limited homology was found between wheat ESTs on homoeologous group 4 and the Arabidopsis genome. Forty-two percent of the homoeologous group 4 ESTs could be classified into functional categories on the basis of blastX searches against all protein databases. (shrink)

SummaryThe present analysis compares the distribution of surnames by means of spatial autocorrelation analysis in the Spain–Portugal border region. The Spanish National Institute of Statistics provides a database of surnames of residents in the western Spanish provinces of Zamora, Salamanca, Cáceres, Badajoz and Huelva. The Spanish and Portuguese patterns of surname distribution were established according to various geographic axes. The results obtained show a low diversity of surnames in this region – especially in the centre – which can be explained (...) by the absence of any major geographic barriers, with the exception of the mountain ranges between hydrographic basins, and by the presence of traditional roads that have existed since Roman times. The latter have resulted in a constant migratory flow over short–median distances, which, as can be deduced from the surnames, fits two north/south territorial axes running parallel to the border between Spain and Portugal. The distribution patterns of Portuguese and Spanish surnames differ with regard to their frequencies in the five provinces studied, which can be attributed to their respective historical, economic and social conditions. It is concluded that the border delimiting these two countries has affected the migratory flow, thereby conditioning the demographic and genetic structure of the western Spanish regions. (shrink)

A total of 944 expressed sequence tags generated 2212 EST loci mapped to homoeologous group 1 chromosomes in hexaploid wheat. EST deletion maps and the consensus map of group 1 chromosomes were constructed to show EST distribution. EST loci were unevenly distributed among chromosomes 1A, 1B, and ID with 660, 826, and 726, respectively. The number of EST loci was greater on the long arms than on the short arms for all three chromosomes. The distribution of ESTs along chromosome arms (...) was nonrandom with EST clusters occurring in the distal regions of short arms and middle regions of long arms. Duplications of group 1 ESTs in other homoeologous groups occurred at a rate of 35.5%. Seventy-five percent of wheat chromosome 1 ESTs had significant matches with rice sequences, where large regions of conservation occurred between wheat consensus chromosome 1 and rice chromosome 5 and between the proximal portion of the long arm of wheat consensus chromosome 1 and rice chromosome 10. Only 9.5% of group 1 ESTs showed significant matches to Arabidopsis genome sequences. The results presented are useful for gene mapping and evolutionary and comparative genomics of grasses. (shrink)